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M94A2603.TXT
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1994-10-25
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Document 2603
DOCN M94A2603
TI Clinical evaluation of different tests for Chlamydia
trachomatis-infection.
DT 9412
AU Petrova E; Borissov I; Dept. of Dermatology and Venerology High Medical
School, Sofia,; Bulgaria.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):267 (abstract no. PB0497). Unique
Identifier : AIDSLINE ICA10/94369972
AB OBJECTIVE: To compare results from three different tests detecting
infection with Chlamydia trachomatis (Chl. tr.) and to evaluate them in
respect to clinical diagnosis for genital-localized infection. MATERIAL
AND METHODS: Serum samples from 368 patients attending STD and
gynecological clinics were examined for presence of anti-Chl. tr.
antibodies in Chlamydia-IgG-EIA (Labsystems, Finland), parallelly with
two antigen-detecting assays: Chlamydia-Ag-EIA (Labsystems) and
Clearview (Unipath, UK). All patients, positive in any test were treated
and followed up for three to five months. RESULTS: Before and after
treatment, results obtained in antigen-tests coincided and often were
contraversial to that of antibody-detecting test. DISCUSSION: The
serological testing for Chl. tr.-antibodies seems not conclusive for
diagnosis of genital infection and effect of treatment. When a positive
result for antibody is found, a thorough clinical examination and
antigen-test should be performed.
DE Adult Antibodies, Bacterial/BLOOD Antigens, Bacterial/BLOOD
*Chlamydia trachomatis/IMMUNOLOGY Chlamydia
Infections/*DIAGNOSIS/TRANSMISSION Comparative Study Female Follow-Up
Studies Human Male Predictive Value of Tests Sexually Transmitted
Diseases, Bacterial/*DIAGNOSIS/TRANSMISSION MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).